Patrick Mahomes Odds to Win MVP & OPOY (September 2025)

Patrick Mahomes Odds to Win MVP, OPOY & Props (September 2025)

Patrick Mahomes, the superstar quarterback for the Kansas City Chiefs, has become a household name in the NFL, thrilling fans and impacting Kansas sportsbooks with his remarkable performances and game-changing plays. Can Mahomes add a third MVP to his resume?

Let's break down everything you need to know about No. 15's odds this season:

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Patrick Mahomes Odds: September 2025

Patrick Mahomes celebrates with Lombardi Trophy

All of the odds shown in the article were sourced from FanDuel Kansas.

Odds will differ at sportsbooks, and according to the odds from FanDuel, Mahomes has the fourth-shortest odds to take home MVP in the 2025-26 season.

👑 MVP Odds:	+650 (13.3% chance)
🏆 OPOY Odds:	+7500 (1.3% chance)
⭐ Most Reg. Season Passing Yards:	+900 (10.0% chance)
🏈 Reg. Season O/U Passing Yards:	4000.5 yds (-114/-114)
⭐ Most Reg. Season Passing TDs:	+1100 (8.3% chance)
🏈 Reg. Season Passing O/U TDs:	27.5 TDs (-114/-114)
🏈 To Record 4,000+ Passing Yards:	-130 (56.5% chance)
📈 To Record 4,500+ Passing Yards:	+280 (26.3% chance)
✅ Odds Last Verified:	September 1, 2025

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Where to Bet on Patrick Mahomes MVP Odds?

Kansas bettors can wager on Patrick Mahomes' MVP odds via all of the best Kansas betting apps.

Among the many options, Fanatics Sportsbook Kansas might offer the best selection of all Mahomes-themed props, though the process for betting on his MVP odds will be the same at most sportsbooks.

However, we recommend you use a Kansas sports betting promo to boost the value of your wager when you do decide to bet.

Chiefs Playoff Chances

Unless Mahomes goes down with an injury, the latest Chiefs playoff chances should remain favorable. As we get closer to the season, the Chiefs have a 79.4% chance to make the playoffs according to -385 odds on FanDuel. This should come as no surprise to anyone who has followed the NFL since Mahomes entered the league.

Chiefs Super Bowl Odds

Similarly, the latest Kansas City Chiefs Super Bowl odds suggests this team is a juggernaut. They currently have the fourth-shortest odds to win the Super Bowl on FanDuel, which would be their third ring in four seasons.

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Patrick Mahomes MVP Odds FAQ

The latest Patrick Mahomes MVP odds are +650, according to FanDuel Kansas. The oddsmakers currently believe Mahomes has a good chance to win the award, which would be the third of his illustrious career.

Patrick Mahomes has won two NFL MVP Awards in his career. His first MVP was in 2018 and again in 2022. Mahomes led the Chiefs to Super Bowl wins in both of those seasons. In 2022, Mahomes led the league in passing yards with 5,250 and TDs with 41.

Patrick Mahomes was a long shot to win MVP in 2018 at +3525 preseason odds. In 2022, Mahomes' MVP odds were +800 before the season began. Both seasons ended with him taking home the award, proving why he’s never a player to count out.

Author

Calli Varner

Calli has been an avid sports fan since she can remember. After earning her Bachelor’s degrees from the Walter Cronkite School of Journalism at Arizona State University, she combined her passion for journalism and sports. Calli has covered the NFL, NBA, MLB, NCAAF, college sports, and sports betting for several media outlets.